Scientists have discovered a new organ involved in the sensation of pain. Researchers have proven that special cells surrounding nerve cells that perceive pain spreading to the outer layer of skin play a role in the sensation of pain. The discovery is expected to contribute to the development of new painkillers.
Scientists said the discovery brings a new perspective to pain and that they can answer long-standing puzzles. According to The Guardian, co-authors of the Karolinska Institutet in Sweden. "The real question for us now is whether these cells are actually the cause of some chronic pain disorders," said Pat, Patriarch of Ernfors.
Researchers at the journal Science, neglecting the nature of cells in the skin, saying, "These cells surround nerve cells. They are the type of Schwann cells that help keep them alive," he said.
The study found that these Schwann cells had an octopus shape. After examining the tissue, the team found that the cell body sits below the outer layer of skin, but that the cells have long extensions wound around the ends of the painful nerve cells that extend to the epidermis.
F In the area of pain, we are talking about free nerve endings that are responsible for feeling pain. But they're not really free ..
The team’s biggest finding was that these Schwann cells could feel the pain. During the study, it was observed that Schwann cells on the skin of the feet of mice produce a protein that is able to absorb light. When light shines on cells, this protein changes and affects the membrane and creates a shift in the electrical charge of cells, in other words stimulating cells.
The neuroscientist explains: ışık When the light shone in these cells, the mice raised their legs. They also acted like licking, jerking off and protecting their claws. This shows that stimulation of Schwann cells causes pain. "
As the duration of light pulses lengthened, the number of nearby nerve cells increased and the idea that these Schwann cells sent a signal through nerve cells to the brain was supported.
Professor McNaughton, a sensory systems expert with King & # 39; s College London, said the study was interesting and radical. McNaughton says: If this is to be found in later studies, this article suggests that pain-sensitive terminal cells do not always manage pain directly, but more [Schwann] there will be a paradigm shift that shows that it can be managed by cells.